Title : Cell Fate Regulation upon DNA Damage: p53 Serine 46 Kinases Pave the Cell Death Road.

Pub. Date : 2019 Dec

PMID : 31621101






2 Functional Relationships(s)
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1 One posttranslational modification of p53, phosphorylation at Serine 46, selectively occurs after severe DNA damage and is envisioned as a marker of the cell death response. Serine tumor protein p53 Homo sapiens
2 In this essay, the current body of evidence on the molecular function of this deadly p53 mark, its evolutionary conservation, and the regulation of the key players of this response, the p53 Serine 46 kinases, are reviewed and dissected. Serine tumor protein p53 Homo sapiens