Pub. Date : 2019
PMID : 31482012
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In addition to doxorubicin, our results here indicated that camptothecin and bortezomib, which are a topoisomerase 1 poison and a 26 S proteasome inhibitor, respectively, could also induce apoptosis in a p53-dependent manner in prostate cancer. | Bortezomib | tumor protein p53 | Homo sapiens |
| 2 | In contrast, p53-mediated apoptosis from bortezomib-induced stress is transcription-dependent. | Bortezomib | tumor protein p53 | Homo sapiens |
| 3 | We then investigated the p53 ratio of nucleus to cytosol corresponding to low and high dose doxorubicin, camptothecin, or bortezomib treatment. | Bortezomib | tumor protein p53 | Homo sapiens |