Title : SCF(FBXW7)-mediated degradation of p53 promotes cell recovery after UV-induced DNA damage.

Pub. Date : 2019 Oct

PMID : 31337255






1 Functional Relationships(s)
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1 We identified a hitherto-unknown FBXW7-interacting protein, p53, which is phosphorylated by glycogen synthase kinase 3 at serine 33 and then ubiquitylated by SCF(FBXW7) and degraded. Serine tumor protein p53 Homo sapiens