Title : Far-red light-mediated programmable anti-cancer gene delivery in cooperation with photodynamic therapy.

Pub. Date : 2018 Jul

PMID : 29680675






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Short-time (8-min) light irradiation produced non-lethal amount of ROS to disrupt the endosomal membranes and facilitate p53 gene release via degradation of TK-PEI, which collectively enhanced p53 expression levels toward anti-cancer gene therapy. ros tumor protein p53 Homo sapiens
2 Short-time (8-min) light irradiation produced non-lethal amount of ROS to disrupt the endosomal membranes and facilitate p53 gene release via degradation of TK-PEI, which collectively enhanced p53 expression levels toward anti-cancer gene therapy. ros tumor protein p53 Homo sapiens
3 Long-time (30-min) light irradiation at the post-transfection state generated lethal amount of ROS, which cooperatively killed cancer cells to strengthen p53 gene therapy. ros tumor protein p53 Homo sapiens