Title : Nutlin-3a selects for cells harbouring TP53 mutations.

Pub. Date : 2017 Feb 15

PMID : 27813088






1 Functional Relationships(s)
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1 In order to improve the selectivity of the HIMA for HUFs harbouring TP53 mutations, we explored the use of Nutlin-3a, an MDM2 inhibitor that leads to stabilisation and activation of wild-type (WT) p53. nutlin 3 tumor protein p53 Homo sapiens