Title : Human T-cell leukemia virus type-1-encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activity of p300/CBP and HBO1.

Pub. Date : 2016 Jan 12

PMID : 26625199






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In HCT116 p53+/+ cells treated with the DNA-damaging agent, etoposide, HBZ reduced p53-mediated activation of p21/CDKN1A and GADD45A expression, which was associated with a delay in G2 phase-arrest. Etoposide tumor protein p53 Homo sapiens
2 In HCT116 p53+/+ cells treated with the DNA-damaging agent, etoposide, HBZ reduced p53-mediated activation of p21/CDKN1A and GADD45A expression, which was associated with a delay in G2 phase-arrest. Etoposide tumor protein p53 Homo sapiens