Pub. Date : 2014 Dec
PMID : 25474278
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | PURPOSE: The aim of this study was to evaluate the prognostic value of MSI-H and p53 overexpression in metastatic colorectal cancer (mCRC) treated with oxaliplatin and fluoropyrimidine-based first line chemotherapy. | Oxaliplatin | tumor protein p53 | Homo sapiens |
2 | mCRC patients with p53 overexpression undergoing an irinotecan containing second- or third-line chemotherapy after oxaliplatin failure have a significantly longer post-progression survival compared to patients without p53 overexpression. | Oxaliplatin | tumor protein p53 | Homo sapiens |