Title : HO-1 up-regulation: a key point in high-risk neuroblastoma resistance to bortezomib.

Pub. Date : 2014 Apr

PMID : 24380881






2 Functional Relationships(s)
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Protein Name
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1 BTZ-treated HTLA-230 cells down-regulated p53 and up-regulated p21, favoring cell survival. Bortezomib tumor protein p53 Homo sapiens
2 The inhibition of HO-1 activity obtained by Zinc (II) protoprophyrin IX (ZnPPIX) was able to significantly increase the pro-apoptotic effect of BTZ in a p53- and p21-independent way. Bortezomib tumor protein p53 Homo sapiens