Title : Importance of ERK activation in As2O3-induced differentiation and promyelocytic leukemia nuclear bodies formation in neuroblastoma cells.

Pub. Date : 2013 Nov

PMID : 24004656






1 Functional Relationships(s)
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1 We used three human neuroblastoma cell lines (SH-SY5Y, IGR-N-91, LAN-1) that differ from their MYCN and p53 status to explore the intracellular events activated by As2O3 and involved in neurite outgrowth, a morphological marker of differentiation. Arsenic Trioxide tumor protein p53 Homo sapiens