Title : Low-dose arsenic induces chemotherapy protection via p53/NF-κB-mediated metabolic regulation.

Pub. Date : 2014 Mar 13

PMID : 23524579






3 Functional Relationships(s)
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1 Low-dose arsenic induces chemotherapy protection via p53/NF-kappaB-mediated metabolic regulation. Arsenic tumor protein p53 Homo sapiens
2 Pretreatment of untransformed cells with low doses of arsenic induced concerted p53 suppression and NF-kappaB activation, which elicited a marked induction of glycolysis. Arsenic tumor protein p53 Homo sapiens
3 Using both in vitro and in vivo models, we demonstrated an absolute requirement of functional p53 in arsenic-mediated protection. Arsenic tumor protein p53 Homo sapiens