Title : Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells.

Pub. Date : 2011 Jul

PMID : 21519790






2 Functional Relationships(s)
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1 Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells. trichostatin A tumor protein p53 Homo sapiens
2 We found that VPA and TSA induce apoptosis, upregulate p21/Waf1/CIP1, repress TMPRSS2-ERG expression and affect acetylation status of p53 in VCaP cells. trichostatin A tumor protein p53 Homo sapiens