Title : Increased susceptibility of spinal muscular atrophy fibroblasts to camptothecin is p53-independent.

Pub. Date : 2009 May 16

PMID : 19445707






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Increased susceptibility of spinal muscular atrophy fibroblasts to camptothecin is p53-independent. Camptothecin tumor protein p53 Homo sapiens
2 Upon camptothecin treatment, levels of p53 were markedly increased. Camptothecin tumor protein p53 Homo sapiens
3 To determine if p53 plays a role in the increased sensitivity of SMA fibroblasts to camptothecin, we analyzed the sensitivity of SMA fibroblasts to another DNA topoisomerase I inhibitor, beta-lapachone. Camptothecin tumor protein p53 Homo sapiens