Title : Novel polymerase chain reaction approach for full-coding p53 mutation detection in microdissected archival tumors.

Pub. Date : 2000 Jun

PMID : 10850547






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1 A novel polymerase chain reaction (PCR) approach for the analysis of the entire p53 coding and splice site regions from microdissected, formalin-fixed, paraffin-embedded tumor tissues has been developed which allows multiple genetic analyses to be performed from one primary amplification reaction. Formaldehyde tumor protein p53 Homo sapiens